Berberine Advanced

Berberine is a natural compound found in plants like barberry and goldenseal. Berberine Advanced uses a high absorption form called Berberine Phytosome™, with 550 mg per capsule, to support healthy blood sugar, insulin sensitivity, appetite control, and weight management in women with PCOS (now also called PMOS).* It was formulated by registered dietitian Tallene Hacatoryan, MS, RD.

Regular berberine is poorly absorbed by the body. Berberine Advanced uses a phytosome form, where berberine is bound to natural phospholipids to help it reach your bloodstream. In a 2021 randomized, double blind, crossover study in healthy volunteers, berberine phytosome was absorbed about 10 times better than the same amount of standard berberine.* That’s why you get meaningful support from just 2 capsules a day.

Berberine is one of the most studied natural compounds for PCOS. Several meta analyses of randomized controlled trials in women with PCOS have found that berberine improves insulin resistance, lowers testosterone, and improves cholesterol, with results similar to metformin for insulin resistance.* Most of those studies used standard berberine, which is why we chose a form that absorbs better.

Take Berberine Advanced twice a day: 1 capsule with breakfast and 1 capsule with dinner, for 2 capsules a day. Always take it with food, which helps your digestion and keeps blood sugar steady. Each bottle is a 30 day supply.

Some women notice steadier energy and fewer carb cravings within the first few weeks. Deeper metabolic benefits build with consistent use, and most women see the biggest changes around 8 to 12 weeks. We recommend giving it a full 90 days.*

Berberine is generally well tolerated, and the high absorption form in Berberine Advanced means a lower daily dose than many standard berberine products. Some people notice mild digestive changes like constipation, loose stools, or cramping, especially at the start. Taking it with meals helps. If you’re sensitive, start with 1 capsule a day for the first week before moving to 2.

No. Berberine is not recommended during pregnancy or while breastfeeding. If you’re trying to conceive, talk with your doctor about whether to continue, and stop taking it once you’re pregnant.

Talk with your doctor or pharmacist first if you take any prescription medication, because berberine can affect how some medications work. This is especially important if you take blood sugar medication such as metformin, insulin, or sulfonylureas, since the combination may lower blood sugar too much. Also check first if you take cyclosporine, blood thinners, blood pressure medication, or other medications processed by the liver, since berberine can change how quickly some drugs are broken down.

Berberine is a natural plant compound sold as a supplement, while metformin is a prescription medication. In head to head trials in women with PCOS, berberine improved insulin resistance about as well as metformin, and some studies also found added benefits for cholesterol and waist size.* They aren’t interchangeable, though. Never stop or swap a prescription without talking to your doctor, and don’t combine them unless your doctor approves, since together they can lower blood sugar too much.

Yes, and many women do. Berberine and inositol work in different ways. Inositol supports insulin signaling, ovulation, and hormone balance, while berberine activates AMPK, your body’s metabolic master switch, to support blood sugar and fat metabolism.* If insulin resistance is your main focus, the Insulin Resistance Bundle pairs a 90 day supply of each. If you take blood sugar medication, check with your doctor before combining them.

No, and it isn’t a substitute for them. Early research suggests berberine may support your body’s own GLP-1 release, the hormone that helps you feel full, which may be one reason many women notice better appetite control.* Prescription GLP-1 medications work in a different and much stronger way.

Yes. Berberine Advanced is vegan friendly and non GMO, with no gluten, dairy, soy, artificial colors, or preservatives.

Berberine Advanced is designed for daily use as part of your routine, and many women in our community take it continuously. If you plan to take it long term, check in with your healthcare provider from time to time, especially if you have other health conditions or take medications.

Every OvaFit order is covered by our 90 day happiness guarantee. If you’re not happy, email [email protected] within 90 days of your purchase and we’ll help you with a refund. Please reach out before sending anything back. Unopened product needs to be returned to us, but opened product does not. Return shipping is paid by the customer, the original shipping cost isn’t refunded, and there’s no restocking fee.

Yes, anytime. Log in to My Account on ovafit.org to delay your next shipment, skip a delivery, or cancel. There are no contracts and no cancellation fees. If you need a hand, email [email protected] and our team will take care of it for you.