Why is Ozempic Gaining Popularity in the PCOS Community?

When people think of polycystic ovary syndrome (PCOS), they often think about irregular menstrual cycles and infertility. But if you have PCOS, you know the symptoms are much broader than that. You most likely deal with fatigue, sleep struggles, and one of the most aggravating symptoms for many Cysters—stubborn weight gain.

And I get it, losing weight with PCOS isn’t as simple as people assume it may be. With root causes like insulin resistance and chronic inflammation, the journey involves much more than counting calories and cutting meals. (Which you shouldn’t be doing anyway, but especially not when you have PCOS!). The good news? Natural, sustainable methods can target and even reduce symptoms.

I’m a huge believer in lifestyle changes that work with your body, not against it. For me (and many other Cysters), that looks like following a gluten- and dairy-free anti-inflammatory diet, adding slow-weighted workouts, managing stress, and taking supplements that support hormone health. These habits don’t just manage symptoms of PCOS; they can help reverse them for good.

But I understand every healing journey is different. Many women turn to their doctors for medication support, with Metformin traditionally being the most common option. Recently, though, more and more women with PCOS are being prescribed Ozempic—a medication originally FDA-approved to treat type 2 diabetes—as an off-label treatment.

While Ozempic can help some women with PCOS lose weight, it’s a temporary fix. And with medications like Ozempic comes a long list of side effects that can leave you feeling worse over time.

If you’re considering Ozempic, keep reading—I’m breaking down whether or not it truly is the best option. (Spoiler alert: natural alternatives can support hormones while also losing weight. All without the side effects!).

Ozempic and PCOS: Exploring PCOS and Available Treatment Options

Ozempic works by mimicking a natural gut hormone called GLP-1 (glucagon-like peptide-1). This gut hormone essentially helps regulate blood sugar and tells your brain when you’re full. Sounds like the perfect solution for weight management, right? But here’s what most people don’t talk about… once you stop the weekly injections, that weight often creeps right back on. And let’s not forget that Ozempic isn’t a quick fix weight loss tool; it’s also an endocrine disruptor. What does that mean? It can throw your hormones even more out of balance, which is the last thing you need when your hormones are already struggling with PCOS.

A study published in the Journal of Endocrinology and Metabolism actually explored the effects of women on PCOS. Here’s what they found:

An average weight loss of 10-15 pounds over 6 months
Improved insulin resistance
More consistent menstrual regularity
Increased fertility markers
Decreased free androgen and increased sex hormone binding globulin (SHBG)

This all sounds amazing, right? The truth is, I’ve seen so many women soar past these odds using sustainable, natural methods. And, on the topic of stubborn weight gain, I’ve seen women using our method lose 10 pounds in one month. This isn’t to say it will work for everyone, or that Ozempic doesn’t work for anyone. But ultimately, every medication needs an exit plan. And in terms of Ozempic, that exit plan results in a loss of improvements, major setbacks, and long-term side effects. For more on this study, check out my video, “The Truth About Ozempic for PCOS Weight Loss!”

You can see why I’m such a big fan of healing your body naturally and supporting your hormones from the inside out. No harsh medications that only mask the symptoms temporarily, just long-term solutions.

What Does Ozempic Do?

Mimics GLP-1 Hormone

Everyone, PCOS or not, naturally produces the GLP-1 hormone. It’s that little signal our guts release after we eat that says, “Hey, I’m full now!” This isn’t the only thing GLP-1 does, though—it also helps regulate blood sugar levels, and inevitably, affects appetite and weight.

So, where does Ozempic come in? Ozempic is what’s known as a GLP-1 agonist. Basically, it just mimics your body’s natural GLP-1 hormone. When taken, it attaches to GLP-1 receptors throughout your body—in your brain, pancreas, and gut.

Then it sends signals to help curb your appetite, slow digestion, and nudge your pancreas to release insulin so your body can turn glucose into energy. The catch? Ozempic is a much stronger, longer-lasting version of that fullness and blood sugar hormone your body already makes. This might sound helpful, but it comes with unwanted side effects like nausea, vomiting, and diarrhea.

Here’s the good news: You don’t need harsh medications to get those benefits. There are natural ways to support your GLP-1 levels and balance your hormones. My favorite? Berberine Advanced. It’s a natural GLP-1 booster that helps curb cravings, support healthy digestion, and promote blood sugar balance—without the needles, harsh side effects, or temporary “fixes.”

All you need is two easy capsules a day paired with a healthy lifestyle. You’ll be amazed at how your body starts to feel better, naturally.

Slows Down Digestion

Ozempic slows down how quickly your body digests food. That’s why so many people say they feel fuller longer and notice fewer cravings or constant hunger. It also helps your body release energy more steadily, avoiding those frustrating blood sugar spikes and crashes.

Sounds great in theory, right? But here’s the part no one talks about…

This delayed digestion—also called delayed gastric emptying—can lead to a pretty serious long-term side effect known as gastroparesis, or stomach paralysis. It means your stomach takes too long to empty food, causing uncomfortable digestive slowdowns, bloating, nausea, and other issues. Many women with PCOS already struggle with gut health, sluggish digestion, or bloating—so this is something to watch out for.

While this side effect is considered rare, it’s a huge reason why I always lean toward natural, gentle options that work with your body.

Noticeable Weight Loss

Since Ozempic reduces appetite, curbs cravings, and helps you feel fuller faster (and longer), it naturally puts you into a calorie deficit. That means the number on the scale will go down, and it’s presumed to be going down fast.

In fact, clinical trials show that nearly 80% of PCOS patients who were considered obese lost at least 5% of their body weight within the first three months on Ozempic. And we know just a 5-10% reduction in body weight can make a significant difference in easing PCOS symptoms.

But here’s the truth… Ozempic is not the only way to lose weight with PCOS. Aside from this, it’s simply just not a permanent solution. As soon as you stop taking the medication, the weight will come back—along with plenty of possible side effects. As a result, many women begin to feel discouraged, frustrated, and overwhelmed.

This doesn’t mean you can’t (or won’t) experience true relief, though. Losing weight, reversing PCOS symptoms, and actually keeping weight off begins with daily habits. Following a PCOS-friendly, gluten- and dairy-free anti-inflammatory meal plan and adding natural supplements like Berberine Advanced and Ovasitol are key ways to improve insulin sensitivity. In turn, this can help your body turn food into energy instead of stubborn fat.

Pair that with some stress management and a few low-impact muscle-building workouts, and you’re setting yourself up for lasting success.

Controls Blood Sugar

Since Ozempic works as a GLP-1 agonist, it helps your body manage blood sugar and improve insulin sensitivity. It basically tells your pancreas how much insulin to release after you eat. This can help prevent blood sugar spikes, crashes, and endless cravings that soon follow.

You don’t need a weekly injection to support your body’s natural insulin response—even if it seems convenient! Through simple, sustainable habits, you can naturally improve insulin sensitivity. Think: low-carb, protein-focused diets, lots of healthy fats, and building muscle with slow-weighted workouts. On top of this, targeted supplements can give your body the extra support it needs. Support hormone balance and glucose control with Berberine Advanced and Ovasitol—so you can finally feel like yourself again—naturally!

Can Ozempic Help with PCOS Symptoms?

Let’s clear something up—Ozempic is not a cure for PCOS. It’s also not an FDA-approved treatment for PCOS. Sure, it might help ease some symptoms, but it doesn’t actually address the root of the problem long-term.

Ozempic works by supporting weight loss and improving insulin resistance, which are two major factors that can contribute to PCOS symptoms. In one study I came across, 27 women with PCOS and obesity took semaglutide for six months. The results? Most of them lost weight, dropping their BMI from 34.4 to 29.4, and about 80% of them started having more regular periods.

But it’s not magic. The reason some symptoms improved wasn’t because Ozempic “cured” PCOS. It’s because weight loss can naturally lower androgen levels, like testosterone, which helps balance your hormones.

And while we’re on the topic of hormone balance… let’s talk about something super important. Ozempic is actually considered an endocrine disruptor. Yep, that means it doesn’t just touch your blood sugar—it can mess with your other hormone levels too. And for us Cysters? That’s the last thing we need.

But (and it’s a big but), as soon as you stop taking the weekly injections, those results can disappear. This is especially true if you’re not actively supporting your body with healthy habits. Why wait for the effects of meds to kick in when you can start healing your body naturally today?

Why is Ozempic Gaining Popularity in the PCOS Community?

You’ve probably heard the buzz about Cysters using Ozempic over the last year. It’s being prescribed off-label PCOS treatment to help with symptoms like weight gain and insulin resistance. And yes—it can help with those things… temporarily.

It’s not a long-term fix. It won’t make your PCOS disappear. And once you stop those weekly injections, most of that progress goes right out the window.

Trust me, I know how frustrating it is to lose weight with PCOS. I’ve been there, too. But here’s my take: it is 100% possible to lose weight naturally—without needles, without harsh side effects, and without feeling like your only option is a prescription.

It takes real lifestyle changes… But the payoff? A healthier body, balanced hormones, and results that actually last.

How Does Ozempic Work for PCOS?

Improve Insulin Sensitivity

Did you know that 80% of women with PCOS also deal with insulin resistance? That means your body struggles to process glucose the right way. Instead of turning it into energy, it stores it as fat, making it really hard to lose weight. This also throws your hormones even further out of balance.

When you support your body in producing the right amount of insulin, you can finally start releasing stubborn body fat and see the scale move. And improving insulin sensitivity doesn’t just help with weight—it also helps lower androgen levels, which is key for balancing hormones.

Ozempic might seem like a fast solution for insulin resistance, but it’s also an endocrine disruptor. Meaning? Sure, it might help with insulin and androgens short term, but it could throw other important hormones totally out of whack.

Support Weight Loss

Losing weight is hands down one of the best ways to start reversing your PCOS symptoms. When people with PCOS lose even a small amount of weight, they often see improvement in those frustrating symptoms.

And yes, Ozempic can help with that… but it’s not permanent. The moment you stop those weekly jabs, your appetite comes roaring back—and so does the weight for many women. That’s because Ozempic isn’t fixing the root of the problem, just masking it.

It’s not a long-term solution. You can’t stay on it forever. That’s why I’m so passionate about teaching Cysters to create real, sustainable habits that help keep the weight off for good. You deserve more than a quick fix—you deserve lasting relief.

Reduce Inflammation

Chronic low-grade inflammation is one of those sneaky root issues fueling PCOS symptoms. It’s linked to everything from stubborn weight gain to hormone imbalance and that constant, frustrating fatigue.

Sure, Ozempic can temporarily help reduce inflammation by improving insulin sensitivity, promoting fat loss (especially around the belly), and lowering inflammatory markers in your body. But these are things you only get the benefit of if you’re actively taking Ozempic.

The good news is that you can lower inflammation naturally, and the results actually last. My go-to ways? Filling my plate with veggies (especially leafy greens), adding in omega-3s with a quality supplement or fatty fish like salmon, staying hydrated, and making stress management a daily priority.

These simple, natural habits don’t just lower inflammation; they help heal your PCOS from the inside out.

How to Get Prescribed Ozempic for PCOS

Talk to your doctor.

If you decide Ozempic feels like the right path for your PCOS journey, you’ll need to chat with your doctor to get a prescription. Most of the time, they’ll want to run some tests first to make sure it’s safe for you to take.

But here’s something to keep in mind: Between the wait for appointments and the out-of-pocket costs (those co-pays add up fast), the whole process isn’t exactly quick or cheap. That’s why I always remind Cysters that natural solutions can be started right at home, often for little to no cost.

Check with your insurance provider.

Since Ozempic is only FDA-approved for treating type 2 diabetes, most insurance companies won’t cover the cost for PCOS. That means if you’re considering it, definitely call your insurance provider first to check.

If it’s not covered? You could be looking at spending $1,000 a month—ouch. That’s a lot of cash for a short-term, band-aid fix. This is especially true when there are natural, budget-friendly ways to start healing your PCOS.

How to Naturally Boost Your GLP-1

High-Protein Meals

Did you know that a high-protein diet can naturally boost your GLP-1 hormone? Yep—no needles, no side effects, just real food working with your body. Boosting GLP-1 naturally helps curb cravings, improve appetite control, and support better insulin sensitivity.

When you eat protein, your gut breaks it down into amino acids, which trigger your intestine’s L-cells to release GLP-1. Pretty cool, right?

To get the benefits, build your meals around lean, whole-food proteins like chicken, turkey, and wild-caught fish. I always recommend aiming for at least 30 grams of protein per meal. This helps you feel full, lose stubborn weight, balance your hormones, and keep your metabolism firing.

Plus, eating enough protein is your best defense against muscle loss during weight loss. This is important for everyone to consider, but even more so if you’re looking to keep insulin sensitivity on track.

Need some inspiration? Grab protein-packed, PCOS-friendly recipes inside The Cysterhood app and start building your hormone-healthy meals today!

Slow-Weighted Workouts

When you build muscle through slow-weighted workouts, you’re not just keeping your body strong—you’re actually boosting your natural GLP-1 production. Your body has its own built-in system to help with appetite control, blood sugar regulation, and cravings.

And muscle? It’s a total metabolic powerhouse. It uses blood sugar for fuel, helps lower insulin resistance, balances hormones, and keeps your metabolism working the way it should. The more muscle you have, the easier it is to lose weight and keep it off naturally.

Plus, strength training fights off inflammation, another major root cause of PCOS. Less inflammation means your GLP-1 receptors work better, your gut functions smoothly, and your hormones can get back in balance.

Need help getting started? The Cysterhood app is full of PCOS-friendly, low-impact strength routines designed to help you build muscle without spiking cortisol.

Natural GLP-1 Boosting Supplements

Let me let you in on a little secret… There are natural ways to boost your GLP-1 levels, support weight loss, and improve insulin sensitivity. And no, it doesn’t involve you turning to medications like Metformin or Ozempic.

Two of my favorite supplements for this? Berberine Advanced and Ovasitol.

These powerful, science-backed supplements are made specifically for women with PCOS who are ready to take control of their health naturally. They can actually get to the root of their symptoms, not just slap on a temporary fix.

Berberine Advanced has been shown to help women with POCS lose 2.3x more weight than lifestyle changes alone. But it doesn’t stop there—it also helps lower inflammation, balance cholesterol, improve gut health, and support ovulation and fertility.

Ovasitol is my go-to for a reason. This supplement works wonders for improving insulin sensitivity, supporting weight loss, boosting fertility, and balancing hormones. It even helps support thyroid health—a huge bonus, since thyroid imbalances are super common in Cysters.

The best part? These supplements work with your body to heal. No harsh side effects. No temporary “quick fix.” Just real, sustainable support to help you feel your best.

Ready to ditch the meds and start healing from the inside out? Berberine Advanced and Ovasitol have your back.

Find a holistic long-term approach to healing your PCOS without a weekly shot.

Listen, I totally get the frustration of dealing with stubborn weight, intense cravings, and the endless hormonal rollercoaster that comes with PCOS. It’s exhausting—and tempting to think a weekly Ozempic shot is the magic answer.

But the truth? Ozempic is not a long-term solution—it comes with side effects and risks. And, the moment you stop taking it, the weight and symptoms come right back.

Berberine Advanced and Ovastil are two of the most powerful, research-backed tools you can use to support you on your PCOS journey, These supplemenents improve insulin sensitivity, reduce cravings, support weight loss, balance hormones, and even boost fertility. And they do it naturally.

Want to lose stubborn PCOS weight? Want to balance blood sugar and reduce cravings? Want to support ovulation, egg quality, and hormone health? Then skip the band-aid solution meds and focus on healing your body—every part of it.

Check out NSF-certified Berberine Advanced and Ovasitol today—and take the first step toward reversing your PCOS naturally, for good. You’ve got this, Cyster!